2006-07: Andrei Loktionov joined HC Lokomotiv Yaroslavl’s system. In Yaroslavl, Loktionov played mainly with the farm team, doing well given his twenty-eight points during the season. In that year he also started playing regularly with Russia-90 national team, constantly in the first lines.
2007-08: Skated in the Ivan Hlinka Tournament and was the team leader in both scoring and plus/minus. Later on he made his debut in the Super League (Russia 1), with one assist in five contests. In April 2008, he starred at the WJC under-18 in Kazan where he centered other highly-touted prospects Nikita Filatov and Kirill Petrov, playing a solid tournament with eight points in six games. Loktionov was chosen in the fifth round, 123rd overall, of the 2008 NHL Draft by the Los Angeles Kings.
2008-09: Loktionov signed with the Kings shortly after being drafted and hit the ground running in North America on the heels of an excellent season with Windsor of the OHL is Loktionov. Loktionov really came on strong the moment the calendar flipped to January, after recovering from a December injury, and took it a step higher in the playoffs. Anchoring the second line for a stacked squad, Loktionov helped lift Windsor into champions of both the OHL and the Memorial Cup, scoring 33 points in 20 games, second only to teammate Taylor Hall.
2009-10: In his first professional season, Loktionov posted 9 goals and 15 assists in 29 games with the Machester Monarchs. He also posted a goal and 8 assists in 16 playoff games. The Russian center made his NHL debut on November 25th in a game against the Oilers where he in 15 shifts he logged 11:52 in ice time.
2010-11: Loktionov began the year with the Kings, appearing in seven games before being sent to the AHL's Manchester Monarchs, and was also with Los Angeles in January and February. In 19 games with the Kings he scored 4 goals with 3 assists and was +2 with 2 PMs; averaging just under 15 minutes of ice time per game. Loktionov scored at nearly a point per game pace in 34 games with the Monarchs, scoring 8 goals with 23 assists before suffering a season-ending shoulder injury iin late February. Loktionov's +16 plus/minus was the team's third best.
2011-12: Loktionov split the year between the Kings and their AHL affiliate Manchester — skating in 39 games with the Kings after being re-called in November before returning to the Monarchs in February 2012. He returned to the Kings for the playoffs; appearing in two games. Loktionov scored 3 goals with 4 assists and was minus-four with 2 penalty minutes during the regular season while averaging 12:31 minutes of ice time. He had no points or penalty minutes, averaging 4 minutes of ice time, in the playoffs. Loktionov played 32 AHL games with the Monarchs; scoring 5 goals with 15 assists and was plus-four with 10 penalty minutes.
Loktionov is a solid two-way player who can fulfill various roles on the team ranging from a defensive expert on shorthanded units to a playmaker on a power-play unit. He sees the ice well and effectively uses his linemates, creating a number of scoring chances. A couple of more significant improvement areas for Loktionov include his faceoff skills and his scoring ability. Specifically in regards to his scoring ability, while always a danger in the offensive zone, Loktionov prefers to pass rather than shoot and in a shot-filled North American style of hockey a more multi-dimensional game would make him more dangerous and hard to contain.
Loktionov was dealt by the New jersey Devils to the Carolina Hurricanes at the 2014 NHL Trade Deadline.