2007-08: Andrew Agozzino made his OHL debut with the Niagara IceDogs as a 16-year old and played for Canada Ontario in the 2008 U17 World Hockey Challenge. He scored 12 goals in 10 games and was +3 with 47 penalty minutes in 50 games with Niagara. The IceDogs finished second in the Central Division and reached the second round in the playoffs. Agozzino did not play in any playoff games. He scored 5 goals with 2 assists and had 12 penalty minutes in six games as Canada Ontario captured the gold medal at the WHC.
2008-09: Agozzino was the leading scorer for Niagara in his second OHL season. He scored 27 goals with 29 assists in 67 games and was -10 with 88 penalty minutes. The IceDogs finished fourth in the Central Division but reached the second round in the playoffs after finishing under .500. Agozzino scored 6 goals with 5 assists in 12 playoff games and was -5 with 24 penalty minutes.
2009-10: Agozzino played for the Columbus Blue Jackets in the Traverse City rookie camp but was not signed to a contract and returned to Niagara for his third season with the IceDogs. He made his pro hockey debut at the end of the season – playing in two April games for the American Hockey League's Peoria Rivermen on an amateur tryout contract. He was +1 with no points nor penalty minutes with Peoria. Agozzino was named a team captain for Niagara during the season and was the IceDogs' leading scorer for the second straight year. He scored 37 goals with 29 assists in 66 games and was +15 with 95 penalty minutes. Niagara finished fourth in the Central Division and played the Ottawa 67's in the first round of the playoffs. Agozzino scored 3 goals with 2 assists in five playoff games and was -6 with 15 penalty minutes.
2010-11: Agozzino attended the Tampa Bay Lighting's prospect camp before returning to Niagara for his fourth OHL season. The IceDogs were one of the NHL's top teams with big name prospects like Ryan Strome (NYI) and brothers Freddie and Dougie Hamilton (San Jose and Boston) and finished second in the Central Division. Agozzino was the third- leading scorer for Niagara with a team-leading 43 goals and 31 assists in 68 games and was +32 with 73 penalty minutes. The IceDogs advanced to the Eastern Conference finals against Mississauga-St. Michael's. Agozzino scored 11 goals with 7 assists in 20 playoff games and was +4 with 16 penalty minutes.
2011-12: Agozzino returned to Niagara for a fifth season and was the team's leading scorer. In 67 games he scored 40 goals with 48 assists and was +32 with 67 penalty minutes. The IceDogs finished first in the Central Division and reached the OHL Finals against London. Agozzino scored 11 goals with 7 assists in 20 playoff games and was +4 with 16 penalty minutes.
2012-13: Agozzino was signed to an AHL contract by Colorado AHL affiliate Lake Erie and was the team's leading scorer in his first pro season. He scored 20 goals with a team-high 32 assists in 76 games and was +16 with 73 penalty minutes. Lake Erie finished third in the North Division but missed the AHL playoffs. Agozzino was signed to a two-year, entry-level contract by Colorado in March, 2013.
Signed as a free agent by Colorado on March 22nd, 2013.