2009-10: Andrey Makarov skated in 22 games for Lada Togliatti in Russia's U22 MHL and represented Russia in the 2010 U17 World Hockey Challenge. Makarov had a 4.04 goals against and .874 save percentage for a Lada team that won just 11 of 54 games and was last in the West Conference. Makarov was 2-2 with 1 shutout and had a 3.50 goals against and .920 save percentage in four games for Russia at the WHC. He was selected by Atlant Mytishchi in the second round (25th overall of the 2010 KHL Draft and taken by Lewiston (QMJHL) in the first round (42nd overall) of the CHL Import Draft.
2010-11: Makarov appeared in 27 games for Lewiston as a back-up to over-age goalie Nicolas Champion in his first season in North America. He was 11-14 with 2 shutouts and had a 3.37 goals against and .890 save percentage. Lewiston finished second in the East Division and advanced to the playoff semifinals. Makarov appeared in three playoff games, stopping 51 of 57 shots, and was 0-1 with a 3.40 goals against and .895 save percentage. Makarov was not selected in the 2011 NHL Draft in his first year of eligibility.
2011-12: Makarov went from the QMJHL to the WHL; joining the Saskatoon Blades after Lewiston folded. He skated in 54 games for the Blades – missing time to play for Russia at the 2012 U20 World Junior Championship. Makarov was named the team's Most Valuable Player after going 29-23 with 2 shutouts. He posted a 2.01 goals against and .913 save percentage. The Blades finished third in the East Division. In the Blades' four-game playoff series with Medicine Hat he was 0-4, with one loss coming in overtime, and had a 4.10 goals against and .872 save percentage. Makarov was 1-1 appearing in three games for Russia with a 0.88 goals against and .979 save percentage. Andrei Vasilevski played most of the tournament but Makarov got the start in the gold medal game against Sweden. Makorov stopped 57 of 58 shots as Russia lost to Sweden, 1-0, in overtime. He was invited to the NHL Draft Combine and ranked seventh amongst North American goalies in Central Scouting's final rankings prior to the 2012 NHL Draft.
Makarov is a goaltender that relies on his athleticism to get the job done. Where he needs to show improvement is with the finer points of the position, such as playing the angles well and challenging shooters more often. He has shown adaptability through his transition from Russia to the QMJHL in 2010-11, then the QMJHL to the WHL this past season.
Makarov signed a contract with the Buffalo Sabres but will spend the 2012-13 season playing in the WHL.