2008-09: Matt Mangene played 43 games for the New Hampshire Junior Monarchs in his second season in the Eastern Junior Hockey League. He scored 12 goals with 25 assists and had 39 penalty minutes. The Monarchs captured USA Hockey's U-20 national championship. Mangene committed to playing college hockey at the University of Maine.
2009-10: Mangene played in 29 games for Maine as a freshman, missing ten games due to an injury. He scored 1 goal with 10 assists and was minus-four with 10 penalty minutes. Maine turned things around after starting 1-5 to finish fourth in Hockey East. The Black Bears reached the Hockey East championship game – falling to eventual Frozen Four champion Boston College in a wild 7-6 overtime game.
2010-11: Mangene appeared in all 36 games for Maine as a sophomore. He scored 3 goals with 7 assists and was minus-five with 42 penalty minutes. Maine slipped to fifth in Hockey East and was swept by Merrimack in the playoff quarterfinals.
2011-12: Mangene made his pro hockey debut with Flyers AHL affiliate Adirondack and signed a two-year entry-level contract with Philadelphia in March 2012 following his junior season at Maine. He was scoreless with no penalties in five games for the Phantoms, who finished fifth in the Northeast Division and missed the AHL playoffs. Shifting from defense to the wing in early December, he scored 16 goals with 18 assists and had 58 penalty minutes in 40 games during the college season. Maine reached the Hockey East championship game for the second time in three years (and again lost to eventual national champion BC) and earned the school's first NCAA tournament berth since 2006-07.
Mangene is playing for the ECHL's Trenton Titans in 2012-13. It appears he has been switched from defense to right wing, but this may be just a temporary move.