2006-07: Max Nicastro played for the LA Junior Kings Midget AAA U-18 team. Selected by the Indiana Ice in the 6th round of the 2006 USHL Entry Draft with the 68th overall pick. The Ice traded his rights to the Chicago Steel at the trade deadline.
2007-08: In his second season with the Chicago Steel (USHL), Nicastro recorded 20 points (6g+14a) in 58 appearances. He racked up another goal and two assists in seven postseason games with the club. Played for Team USA at the 2007 World Junior A Challenge.
2008-09: Nicastro played a second year at the junior level with the Chicago Steel in the USHL. In 57 games, the blueliner scored 9 goals, 22 assists for 31 points. He also added 84 PIMs.
2009-10: As a freshman at Boston University, Nicastro scored 3 goals, 12 assists for 15 points in 37 games.
2010-11: During 38 games with Boston University he posted 5 goals and 4 assists for 9 points. While he regressed offensively, he shored up his defensive game and increased his physical play.
2011-12: Nicastro was dismissed from the Boston University hockey team in February after being charged with a criminal act. In 27 games prior to his arrest, he scored 3 goals with 6 assists and was minus-two with 32 penalty minutes. Boston University reached the Hockey East semifinals after finishing third in the regular season and lost to Minnesota in the NCAA West regional. The charges against Nicastro were dropped in June 2012 and he signed a two-year entry-level contract with the Red Wings in July 2012.